Lavrov stressed that the unstable situation in Syria may trigger other consequences which neither Russian Federation nor its European neighbors need.
And The Russian Center for the Reconciliation of Opposing Sides in Syria reportedly examined Douma on Monday and found no traces of chemical weapons.
Syria has been engaged in a brutal civil war since 2011, with dictator Bashar al-Assad accused of several war crimes - including the use of illegal chemical weapons against civilians.
Moscow also said it was calling an emergency session of the United Nations Security Council, where it is a permanent member, to discuss the "aggressive actions" of the U.S. and its allies.
The current escalation of the situation in Syria "has a destructive effect on the whole system of global relations", the Kremlin said.
"First, the Syrian people was subjected to Arab Spring, then Islamic State [IS, formerly ISIS, ISIL], now to 'smart" American missiles.
She blamed "all those who claim moral leadership in this world, who declare their exceptionalism" for the attack, noting that "you should be really exceptional" to attack Syria at a time 'when it was given a chance for a peaceful future'.
The White Helmets are not the sole source of information about the Douma attack.
Ms Zakharova also claims Western media is partly responsible for the attacks.
Russia's ambassador to the United States warned that there would be consequences for the US-led military strikes, adding that it was not acceptable to insult Russia's President.
"All responsibility for them rests with Washington, London and Paris".
"Our warnings have been left unheard", he said.
The ministry has strongly condemned the US-led military action against Syria, calling it an "act of aggression", which violates the UN Charter. "Again, we are being threatened".
Earlier on Friday, the Russian Defense Ministry announced that found individuals who participated in recording the video that was used as evidence of the alleged chemical attack in Douma, Eastern Ghouta, and that it has evidence proving Britain's direct involvement in setting up this incident. They are due to arrive in Syria Saturday to investigate.
"We are interested in meeting experts there to carry out necessary tests".