Given the high stakes amid the fight for local bragging rights, the crowd of over 80,000 are certain to make it a frenzied occasion.
"I know that, at the moment, we perform well, we feel strong and we're not scared to play any team, be it Arsenal or whichever team it is".
But when he takes his Arsenal team to Wembley on Saturday it will be with a rather different approach: hoping that his two big new signings, Pierre-Emerick Aubameyang and Henrikh Mkhitaryan, continue to settle as well as they did last Saturday. "But Thierry came a bit more to the ball as well, participated more in the game".
"First of all we have to win lots of games". We still haven't replaced Viera, Campbell and Keown from the past Arsenal teams who were born leaders.
Arsenal spent too much time "waiting for something to happen" as Harry Kane's second-half strike doomed the Gunners to a 1-0 loss to Tottenham, according to Hector Bellerin. They have won their last nine games at the national stadium, including a penalty shoot-out victory over Chelsea in this season's Community Shield.
But, besides the scoreline at the Emirates, the injection of positivity surrounding Wenger's winter acquisitions can not be understated after a year of headlines dominated by potential want-away stars on expiring contracts. "What you want is that everybody focuses on winning the game".
Defeating Arsenal would help that ambition, while carrying the added bonus of derailing Arsenal. Unfortunately, we weren't able to bring any replacements in and I think that will eventually cost us. "Of course we're going to fight for that to happen", Pochettino said.