Defeat will seriously dent their chances of playing Champions League football next season.
Chelsea have lost further ground to teams above them in the Premier League and are just clinging on to a top four place at the moment with Tottenham snapping at their heels in fifth. "Every week there are three games". "In my life, I like to be a victor and I am a victor", said the Italian.
But whoever's in the dugout for Chelsea, City face a challenge as they are still competing in four competitions and could have some exhausted legs on the field come the business end of the season.
They look set to miss out on a Premier League trophy again this year but face lowly Ostersunds in the Europa League.
Conte has repeatedly voiced his displeasure at the club's recruitment strategy following the departure of key players in Chelsea's title-winning campaign such as Diego Costa and Nemanja Vidic.
"I think obviously there seems to be a few issues with [Antonio] Conte but I'm sure they'll get sorted out and they've got enough quality there to finish in the top four".
"That's why we love football". "This season we are not the same as last season, of course, and they are very good but in the end it is a cup tie and you never know what happens".