However, the opening goal did arrive in the 20th minute as Llorente finally got on the board for Spurs, with the Spaniard turning his marker on the edge of the six-yard box before firing into the bottom corner.
"It's important for him", admitted Spurs boss Pochettino. "When you are a striker you need to feel the net".
"It's a game that only provides us with the opportunity to play with some players that need to be ready if we need them".
"Of course, he is disappointed because when he plays he didn't score but I am sure he is going to help the team". "He has been helping a lot but now with more confidence and belief he is going to help more".
Spurs continued to pour forward and Son doubled their advantage eight minutes before the break when the South Korean played a one-two with Llorente before firing a low drive into the corner of the net.
And 10 minutes from the end French winger Georges-Kevin N'Koudou made the most of his rare appearance in the starting line-up with a deflected goal to wrap up a routine 3-0 win.
He added: "I'm very happy, for different players had a different opportunity to play and show their quality". In fact, you can get odds of 10/1 on Apoel Nicosia winning.
"I think always it's important to assess the players and be sure that some players need to rest because they are so exhausted and they need to breathe a little bit".
A 3-0 victory over an ineffective APOEL on Wednesday took the team to 16 points, the highest total of any team this season, and first place in Group H ahead of holder Real Madrid. "I think all the opponents that it is possible we could have in the draw will be strong and good teams but difficult to know and difficult because all the opponents I think they will be difficult opponents".