"The doctors and the trainers have made a decision to give him a cortisone shot to kind of take away some of that inflammation that's been happening", Chris Ballard said.
Ballard said Wednesday Luck's rehab work is still "going well". "It's the soreness that we're dealing with right now that we've got to get through".
"We're going to try to shut him down and calm it down for right now", Ballard said. "His long-term success is at what we're looking for".
Ballard confirmed Luck was suffering soreness in his shoulder and had been given a cortisone shot to help with pain management.
As a result Luck will not practice this week, and his status for the 2017 season appears to be up in the air at this point.
Colts owner Jim Irsay announced it January that Luck would be ready for the season after undergoing shoulder surgery, but now many wonder if No. 12 will even see the field this season. "I'm not going to put a timeline on that".
Luck said last week that he thought the finish line was in sight with his rehab.
Jacoby Brissett, whom the Colts acquired via trade with New England on September 1, has started the last five games.