Newcastle United will deploy the 4-3-3 formation, with Atsu linking up in attack alongside Spanish youngster Ayoze Perez and last season's top scorer Dwight Gyale as the front three.
Shelvey trod on the right foot of Alli, who was sitting on the ground, as he tried to resume play after a free kick had been awarded. The Dane's pass by met by an on rushing Alli who slotted past Rob Elliot.
Kieran Trippier's injury forced perhaps the most intriguing selection on the day, with Tottenham youngster Kyle Walker-Peters earning his first ever start - or any minutes whatsoever - at the senior level.
Moussa Sissoko was booed as his return to St James' Park ended with Son Heung-min taking his place before the hour mark, and Tottenham soon made their extra man count.
The Toon midfielder was given his marching orders in the second half of the Premier League clash on Sunday after leaving one on Alli, causing widespread confusion over his freaky decision.
The first half didn't exactly go as smoothly as planned, but a Newcastle red card early in the second half opened things up nicely for Spurs.
Newcastle club legend Alan Shearer labelled Shelvey as "pathetic" whilst Sky commentator Alan Smith believed it was one of the most stupid dismissals he has ever seen. - Ben Davies has scored twice in his last two Premier League appearances, as many as in his previous 102 combined.